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1

HCV-Induced Immune Responses Influence the Development of Operational Tolerance After Liver Transplantation in Humans

Bohne, F., Londono, M.-C., Benitez, C., Miquel, R., Martinez-Llordella, M., Russo, C., Ortiz, C., Bonaccorsi-Riani, E., Brander, C., Bauer, T., Protzer, U., Jaeckel, E., Taubert, R., Forns, X., Navasa

Journal:

Science Translational Medicine

Year:

2014

Language:

english

File:

PDF, 695 KB

english, 2014

2

ATG-Fresenius Treatment and Low-Dose Tacrolimus: Results of a Randomized Controlled Trial in Liver Transplantation

C. E. Benítez, I. Puig-Pey, M. López, M. Martínez-Llordella, J. J. Lozano, F. Bohne, M. C. Londoño, J. C. García-Valdecasas, M. Bruguera, M. Navasa, A. Rimola, A. Sánchez-Fueyo

Journal:

American Journal of Transplantation

Year:

2010

Language:

english

File:

PDF, 343 KB

english, 2010

3

Following clinical liver transplantation, the majority of circulating cells exhibiting donor MHC are “cross-dressed” not “passenger” leukocytes

Mastoridis, S., Sanchez-Fueyo, A., Martinez-Llordella, M.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 234 KB

english, 2018

4

Multiparametric Analysis of Circulating Exosomes and Other Small Extracellular Vesicles by Advanced Imaging Flow Cytometry

Mastoridis, Sotiris, Bertolino, Giuliana Minani, Whitehouse, Gavin, Dazzi, Francesco, Sanchez-Fueyo, Alberto, Martinez-Llordella, Marc

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 4.39 MB

english, 2018

5

Characterization of γδ T cell subsets in organ transplantation

Isabel Puig-Pey, Felix Bohne, Carlos Benítez, Marta López, Marc Martínez-Llordella, Federico Oppenheimer, Juan José Lozano, Juan González-Abraldes, Giuseppe Tisone, Antoni Rimola, Alberto Sánchez-Fuey

Journal:

Transplant International

Year:

2010

Language:

english

File:

PDF, 332 KB

english, 2010

6

Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family

Hélène Bour-Jordan, Jonathan H. Esensten, Marc Martinez-Llordella, Cristina Penaranda, Melanie Stumpf, Jeffrey A. Bluestone

Journal:

Immunological Reviews

Year:

2011

Language:

english

File:

PDF, 442 KB

english, 2011

7

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

Zhou, Xuyu, Bailey-Bucktrout, Samantha L, Jeker, Lukas T, Penaranda, Cristina, Martínez-Llordella, Marc, Ashby, Meredith, Nakayama, Maki, Rosenthal, Wendy, Bluestone, Jeffrey A

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 680 KB

english, 2009

8

Multiparameter Immune Profiling of Operational Tolerance in Liver Transplantation

M. Martínez-Llordella, I Puig-Pey, G. Orlando, M. Ramoni, G. Tisone, A. Rimola, J. Lerut, D. Latinne, C. Margarit, I. Bilbao, S. Brouard, M. Hernández-Fuentes, J. -P. Soulillou, A. Sánchez-Fueyo

Journal:

American Journal of Transplantation

Year:

2007

Language:

english

File:

PDF, 402 KB

english, 2007

9

Comparison of Transcriptional and Blood Cell-Phenotypic Markers Between Operationally Tolerant Liver and Kidney Recipients

J. J. Lozano, A. Pallier, M. Martinez-Llordella, R. Danger, M. López, M. Giral, M. C. Londoño, A. Rimola, J. P. Soulillou, S. Brouard, A. Sánchez-Fueyo

Journal:

American Journal of Transplantation

Year:

2011

Language:

english

File:

PDF, 274 KB

english, 2011

10

A yeast-based assay reveals a functional defect of the Q488H polymorphism in human Hsp90α

Morag J. MacLean, Marc Martínez Llordella, Nathalie Bot, Didier Picard

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 450 KB

english, 2005

11

Self-antigen-Driven Activation Induces Instability of Regulatory T Cells during an Inflammatory Autoimmune Response

Bailey-Bucktrout, Samantha L., Martinez-Llordella, Marc, Zhou, Xuyu, Anthony, Bryan, Rosenthal, Wendy, Luche, Herve, Fehling, Hans J., Bluestone, Jeffrey A.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.02 MB

english, 2013

12

P890 SPECIFIC PHENOTYPE AND GENE EXPRESSION PROFILES OF COMBINED LIVER AND KIDNEY TRANSPLANTED PATIENTS IN PERIPHERAL BLOOD MONONUCLEAR CELLS

Dumontet, E., Danger, R., Vagefi, P., Londoño, M.-C., Pallier, A., Lozano, J.J., Giral, M., Degauque, N., Martínez-Llordella, M., Latournerie, M., Boudjéma, K., Dulong, J., Tarte, K., Soulillou, J.-P.

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 65 KB

english, 2014

13

The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance

Waterfield, Michael, Khan, Imran S, Cortez, Jessica T, Fan, Una, Metzger, Todd, Greer, Alexandra, Fasano, Kayla, Martinez-Llordella, Marc, Pollack, Joshua L, Erle, David J, Su, Maureen, Anderson, Mark

Journal:

Nature Immunology

Year:

2014

Language:

english

File:

PDF, 1.23 MB

english, 2014

14

Prospective multicenter clinical trial of immunosuppressive drug withdrawal in stable adult liver transplant recipients

Benítez, Carlos, Londoño, María-Carlota, Miquel, Rosa, Manzia, Tommaso-Maria, Abraldes, Juan G., Lozano, Juan-José, Martínez-Llordella, Marc, López, Marta, Angelico, Roberta, Bohne, Felix, Sese, Pilar

Journal:

Year:

2013

Language:

english

File:

PDF, 564 KB

english, 2013

15

Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo

Yadav, M., Louvet, C., Davini, D., Gardner, J. M., Martinez-Llordella, M., Bailey-Bucktrout, S., Anthony, B. A., Sverdrup, F. M., Head, R., Kuster, D. J., Ruminski, P., Weiss, D., Von Schack, D., Blue

Journal:

Journal of Experimental Medicine

Year:

2012

Language:

english

File:

PDF, 2.25 MB

english, 2012

16

Corrigendum: The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance

Waterfield, Michael, Khan, Imran S, Cortez, Jessica T, Fan, Una, Metzger, Todd, Greer, Alexandra, Fasano, Kayla, Martinez-Llordella, Marc, Pollack, Joshua L, Erle, David J, Su, Maureen, Anderson, Mark

Journal:

Nature Immunology

Year:

2014

Language:

english

File:

PDF, 98 KB

english, 2014

17

End-stage renal disease: Dual transplantation—the immunological role of the liver

Martinez-Llordella, Marc, Sanchez-Fueyo, Alberto

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2014

Language:

english

File:

PDF, 649 KB

english, 2014

18

Upregulation of miR-142-3p in Peripheral Blood Mononuclear Cells of Operationally Tolerant Patients with a Renal Transplant

Danger, R., Pallier, A., Giral, M., Martinez-Llordella, M., Lozano, J. J., Degauque, N., Sanchez-Fueyo, A., Soulillou, J.-P., Brouard, S.

Journal:

Journal of the American Society of Nephrology

Year:

2012

Language:

english

File:

PDF, 992 KB

english, 2012

19

In autoimmune hepatitis type 1 or the autoimmune hepatitis-sclerosing cholangitis variant defective regulatory T-cell responsiveness to IL-2 results in low IL-10 production and impaired suppression

Liberal, Rodrigo, Grant, Charlotte R., Holder, Beth S., Cardone, John, Martinez-Llordella, Marc, Ma, Yun, Heneghan, Michael A., Mieli-Vergani, Giorgina, Vergani, Diego, Longhi, Maria Serena

Journal:

Year:

2015

Language:

english

File:

PDF, 1.34 MB

english, 2015

20

CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response

Martinez-Llordella, M., Esensten, J. H., Bailey-Bucktrout, S. L., Lipsky, R. H., Marini, A., Chen, J., Mughal, M., Mattson, M. P., Taub, D. D., Bluestone, J. A.

Journal:

Journal of Experimental Medicine

Year:

2013

Language:

english

File:

PDF, 3.87 MB

english, 2013

21

Biomarkers and immunopathology of tolerance

Mastoridis, Sotiris, Martínez-Llordella, Marc, Sanchez-Fueyo, Alberto

Journal:

Current Opinion in Organ Transplantation

Year:

2016

Language:

english

File:

PDF, 214 KB

english, 2016

22

P1311 : Thril; pilot study evaluating the safety and efficacy profile of regulatory T cell therapy in liver transplant recipients

Whitehouse, G.P., Safinia, N., Rebollo-Mesa, I., Lowe, K., Thirkell, S., Fry, L., Androulidakis, A., Martinez-Llordella, M., Hope, A., Aluvihare, V., Fisher, C., Lechler, R., Heaton, N., Lombardi, G.,

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 172 KB

english, 2015

23

TRANSCRIPTIONAL PROFILING OF LIVER GRAFTS IN SPONTANEOUS OPERATIONAL TOLERANCE.

Bohne, F., Martinez-Llordella, M., Lozano, J. J., Lopez, M., Benitez, C., Miquel, R., Tisone, G., Rimola, A., Sanchez-Fueyo, A.

Journal:

Transplantation Journal

Year:

2010

Language:

english

File:

PDF, 284 KB

english, 2010

24

Molecular Characterization of Acute Cellular Rejection Occurring During Intentional Immunosuppression Withdrawal in Liver Transplantation

Bonaccorsi-Riani, E., Pennycuick, A., Londoño, M.-C., Lozano, J.-J., Benítez, C., Sawitzki, B., Martínez-Picola, M., Bohne, F., Martínez-Llordella, M., Miquel, R., Rimola, A., Sánchez-Fueyo, A.

Journal:

American Journal of Transplantation

Year:

2016

Language:

english

File:

PDF, 3.70 MB

english, 2016

25

Peripheral phenotype and gene expression profiles of combined liver-kidney transplant patients

Dumontet, Erwan, Danger, Richard, Vagefi, Parsia A., Londoño, Maria-Carlota, Pallier, Annaïck, Lozano, Juan José, Giral, Magali, Degauque, Nicolas, Soulillou, Jean-Paul, Martínez-Llordella, Marc, Lee,

Journal:

Liver International

Year:

2016

Language:

english

File:

PDF, 1.77 MB

english, 2016

26

Tracking Donor-Reactive T Cells

Martinez-Llordella, Marc, Lechler, Robert

Journal:

Transplantation Journal

Year:

2015

Language:

english

File:

PDF, 97 KB

english, 2015

27

Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment

Kordasti, S., Costantini, B., Seidl, T., Perez Abellan, P., Martinez Llordella, M., McLornan, D., Diggins, K. E., Kulasekararaj, A., Benfatto, C., Feng, X., Smith, A., Mian, S. A., Melchiotti, R., de

Journal:

Year:

2016

Language:

english

File:

PDF, 4.23 MB

english, 2016

28

Interferon Sparing Directly Acting Antiviral (DAA) Therapy for HCV in Decompensated Cirrhosis: Natural Killer Cell (NK) Phenotype is Associated with Non-Response

Childs, K., Merritt, E., Swanson, W., Sanchez-Fueyo, A., Martinez-Llordella, M., Agarwal, K., Carey, I.

Journal:

Journal of Hepatology

Year:

2016

Language:

english

File:

PDF, 106 KB

english, 2016

29

IL-2 Therapy Restores the Impaired Function of Regulatory T Cells Induced by Calcineurin Inhibitors in Liver Transplantation

Whitehouse, G., Gray, E., Mastoridis, S., Kodela, E., Sanchez-Fueyo, A., Martinez-Llordella, M.

Journal:

Journal of Hepatology

Year:

2016

Language:

english

File:

PDF, 49 KB

english, 2016

30

Immunotolerance in Liver Transplantation

Mastoridis, Sotiris, Martinez-Llordella, Marc, Sanchez-Fueyo, Alberto

Journal:

Seminars in Liver Disease

Year:

2017

Language:

english

File:

PDF, 218 KB

english, 2017

31

Immunometabolism

Martinez-Llordella, Marc, Mastoridis, Sotiris

Journal:

Transplantation Journal

Year:

2017

Language:

english

File:

PDF, 950 KB

english, 2017

32

Immunological Predictors of Nonresponse to Directly Acting Antiviral Therapy in Patients With Chronic Hepatitis C and Decompensated Cirrhosis

Childs, Kate, Merritt, Elliot, Considine, Aisling, Sanchez-Fueyo, Alberto, Agarwal, Kosh, Martinez-Llordella, Marc, Carey, Ivana

Journal:

Open Forum Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 407 KB

english, 2017

33

Low Dose Interleukin-2 for Refractory Autoimmune Hepatitis

Lim, Tiong Y., Martinez-Llordella, Marc, Kodela, Elisavet, Gray, Elisabeth, Heneghan, Michael A., Sanchez-Fueyo, Alberto

Journal:

Year:

2018

Language:

english

File:

PDF, 755 KB

english, 2018

34

The capacity of persistent HCV infection to regulate alloreactive T cells responses is reversed following viral eradication

Merritt, E., Childs, K., Carey, I., Agarwal, K., Sanchez-Fueyo, A., Martinez-Llordella, M.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 47 KB

english, 2018

35

Low-dose interleukin-2 expands the number of circulating regulatory T cells in patients with treatment-refractory autoimmune hepatitis

Lim, T.Y., Codela, E., Gray, E., Heneghan, M., Martinez-Llordella, M., Sanchez-Fueyo, A.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 95 KB

english, 2018

36

The main determinant of circulating exosomal miRNA profile across a spectrum of patients with liver injury is the degree of liver failure

Mastoridis, S., Patel, V., Woodhouse, C., Martinez-Llordella, M., Sanchez-Fueyo, A.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 166 KB

english, 2018

37

Emergent Transcriptomic Technologies and Their Role in the Discovery of Biomarkers of Liver Transplant Tolerance

Mastoridis, Sotiris, Martínez-Llordella, Marc, Sanchez-Fueyo, Alberto

Journal:

Frontiers in Immunology

Year:

2015

Language:

english

File:

PDF, 158 KB

english, 2015

38

Successful expansion of functional and stable regulatory T cells for immunotherapy in liver transplantation

Safinia, Niloufar, Vaikunthanathan, Trishan, Fraser, Henrieta, Thirkell, Sarah, Lowe, Katie, Blackmore, Laura, Whitehouse, Gavin, Martinez-Llordella, Marc, Jassem, Wayel, Sanchez-Fueyo, Alberto, Lechl

Journal:

Year:

2016

Language:

english

File:

PDF, 2.29 MB

english, 2016

39

Normothermic machine perfusion (NMP) inhibits proinflammatory responses in the liver and promotes regeneration

Jassem, Wayel, Xystrakis, Emmanuel, Ghnewa, Yasmeen G., Yuksel, Muhammed, POP, Oltin, Martinez-Llordella, Marc, Jabri, Yamen, Huang, Xiaohong, Lozano, Juan J., Quaglia, Alberto, Sanchez-Fueyo, Alberto

Journal:

Year:

2018

Language:

english

File:

PDF, 813 KB

english, 2018

40

IL-2 therapy preferentially expands adoptively transferred donor-specific Tregs improving skin allograft survival

Ratnasothy, Kulachelvy, Jacob, Jacintha, Tung, Sim, Boardman, Dominic, Lechler, Robert Ian, Sanchez Fueyo, Alberto, Martinez-Llordella, Marc, Lombardi, Giovanna

Journal:

American Journal of Transplantation

Year:

2019

Language:

english

File:

PDF, 885 KB

english, 2019

41

Ways Forward for Tolerance-Inducing Cellular Therapies- an AFACTT Perspective

ten Brinke, Anja, Martinez-Llordella, Marc, Cools, Nathalie, Hilkens, Catharien M. U., van Ham, S. Marieke, Sawitzki, Birgit, Geissler, Edward K., Lombardi, Giovanna, Trzonkowski, Piotr, Martinez-Cace

Journal:

Frontiers in Immunology

Year:

2019

Language:

english

File:

PDF, 685 KB

english, 2019

42

FRI-116-Capturing the complexities of the immune system in patients with advanced cirrhosis using a whole blood culture system reveals a robust inflammatory response to endotoxin stimulation

Kronsten, Victoria, Woodhouse, Charlotte, Lim, Tiong Yeng, Martinez-Llordella, Marc, Sanchez-Fueyo, Alberto, Shawcross, Debbie

Journal:

Journal of Hepatology

Year:

2019

File:

PDF, 198 KB

2019

43

Detection of somatic mutations in peritoneal lavages and plasma of endometrial cancer patients: a proof‐of‐concept study

Mayo‐de‐las‐Casas, Clara, Velasco, Ana, Sanchez, Douglas, Martínez‐Bueno, Alejandro, Garzón‐Ibáñez, Mónica, Gatius, Sònia, Ruiz‐Miró, Maria, Gonzalez‐Tallada, Xavier, Llordella, Ivana, Tresserra, Fran

Journal:

International Journal of Cancer

Year:

2020

File:

PDF, 1.19 MB

2020

44

Treg sensitivity to FasL and relative IL-2 deprivation drive Idiopathic Aplastic Anemia immune dysfunction

Lim, Shok Ping, Costantini, Benedetta, Mian, Syed A, Perez Abellan, Pilar, Gandhi, Shreyans A, Martinez Llordella, Marc, Lozano, Juan Jose, Antunes dos Reis, Rita, Povoleri, Giovanni A M, Mourikis, Th

Journal:

Year:

2020

File:

PDF, 3.05 MB

2020

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